About Dr. Shyh-Dar Li



Dr. Shyh-Dar Li, BSc(Pharm), PhD

Angiotech Professor in Drug Delivery



Dr. Shyh-Dar Li received a BSc in Pharmacy from National Taiwan University and a PhD in Pharmaceutical Sciences from University of North Carolina at Chapel Hill. After completing his postdoctoral training at University of California, San Diego, he joined Ontario Institute for Cancer Research and the Leslie Dan Faculty of Pharmacy, University of Toronto as a Principal Investigator and Assistant Professor in 2009. He relocated to the Faculty of Pharmaceutical Sciences at University of British Columbia in 2014 as an Associate Professor. He was promoted to the Angiotech Professor in Drug Delivery at the Faculty in 2019. His research focuses on developing innovative drug delivery technologies to enhance drug targeting with interests in lipid and polymer based nanoparticles and prodrug technologies. His research program has been supported by federal funding including National Institutes of Health (NIH) and Canadian Institutes of Health Research (CIHR). In addition to contributing scholarly publications in peer-reviewed journals, his team has successfully licensed three drug delivery technologies to industry with one in phase II trials for brain cancer therapy. Dr. Li has trained 12 postdoctoral fellows, 8 graduate students and 41 undergraduate students. He serves in several research funding review panels, including Canadian Cancer Society Impact Grants, CIHR and National Cancer Institute of NIH. He is currently the Chair of the Faculty’s Nanomedicine and Chemical Biology Research and Training Program, and also a Research Management Committee member of the Nanomedicine Innovation Network.



Teaching Areas of Interest

Dr. Li is teaching the following courses:

PHAR 321 Physical Pharmacy I

PHAR 323 Physical Pharmacy II

PHAR 515 Nanomedicines

PHRM 100 Foundation of Pharmacy – Pharmaceutics

PHRM 212 Medication Management III – Pharmaceutics


Selected Awards


2nd Year Pharmacy Student Teaching Award (June 2016)


Angiotech Professorship in Drug Delivery


Outstanding Research in Pharmacy as a New Investigator, Association of Faculties of Pharmacy in Canada


Canadian Institutes of Health Research New Investigator Salary Award


New Investigator in Pharmaceutics and Pharmaceutical Technologies, American Association of Pharmaceutical Scientists


GlaxoSmithKline/Canadian Society for Pharmaceutical Sciences Early Career Award


Coalition to Cure Prostate Cancer Young Investigator Award, Prostate Cancer Foundation


Selected Presentations

  • Technology transfer and commercialization: my academic experience. 2017 Bio Tech Talent Symposium. Academia Sinica, Taipei, Taiwan. Dec 30, 2017
  • Lipid-based Nanoparticles: a flexible platform for controlled delivery of drugs. Department of Pharmacokinetics and Biopharmaceutics. Tokushima University. Tokushima, Japan. Dec 19, 2017
  • A Polymeric Conjugate Platform for Tumor-targeted Delivery of insoluble drugs. 2017 EuroSciCon Recent Trends in Novel Drug Delivery System. Nov 8, 2017
  • Intelligent anticancer drugs and precision medicine. 2017 Health China Conference in Pharmaceutical Innovation. Nanjing, China. September 13, 2017
  • Nanoparticle drug delivery overcomes multidrug resistance in tumors. 2017 International Conference on Challenges in Drug Discovery and Delivery. Pilani, India. March 3, 2017
  • Targeted drug delivery by lipid nanoparticles. College of Pharmacy, National Taiwan University. Taipei, Taiwan. Dec 26, 2016
  • Manufacturing Headaches: The Gap between Academic Vision and Industry Reality. 2016 Annual Meeting of American Association of Pharmaceutical Scientists, Denver, CO, November 15, 2016
  • Development of a child-friendly oral formulation for an anti-malarial drug. 2016 Targeted Drug Delivery and Prodrug Town Hall Meeting, American Association of Pharmaceutical Scientists, Denver, CO, November 14, 2016
  • Liposomes as a platform technology for drug delivery. Progress In the Theme of Childhood Diseases Seminar, BC Children’s Hospital, Vancouver, BC, November 3, 2016
  • Self-assembled Polymeric Nanoparticles for Drug Targeting to Tumors. Precision Nanosystems Inc. Webinar, May 18th, 10:30-11:30 am PDT, 2016.
  • Rational Design of a Nanoparticle-Drug Conjugate for Tumor Targeting. 2015 AAPS annual meeting, Orlando, FL. Nov 28, 2015.
  • Nanoparticle-based Drug Delivery for Anticancer Drugs. University of British Columbia, Vancouver, BC, April 30, 2014
  • Pharmaceutical Engineering of Multifunctional Nanoparticles for Enhanced Cancer Therapy. Soochow University, Shanghai Jiaotong University, Zhejiang University, China January 6-10, 2014
  • Targeted Cancer Chemotherapy Enabled by Nanoengineering. South University of Science and Technology of China, Shenzen, China, December 27, 2013
  • Pharmaceutical Engineering of Polymeric Nanoparticles for Delivering Water Insoluble Cytotoxic Drugs. American Association of Pharmaceutical Scientists, San Antonio, TX, November 11, 2013
  • NanoCMC: a nanoparticle platform for targeted delivery of water insoluble drugs. University of British Columbia, Vancouver, BC, November 1, 2013
  • Cancer Chemotherapy by Multifunctional Nanoparticles. University of Houston, Houston, TX, August 21, 2013
  • Tumor Stromal Depletion by a Docetaxel-incorporated Nanoparticle. Gordon Research Conference: Cancer Nanotechnology, West Dover, VT, July 15, 2013
  • Multifunctional Nanoparticles for Targeted Delivery of Anticancer Drugs. Canadian Society for Pharmaceutical Sciences, Vancouver, British Columbia, June 14, 2013
  • Get Prepared for a Faculty Position at a Research-intensive University. UNC Eshelman School of Pharmacy, Alumi Connection Forum, Chapel Hill, North Carolina, May 17, 2013
  • Modulation of Tumor Microenvironment by a Taxane Nanoparticle. Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, May 16, 2013
  • Targeting Cancer-Associated Fibroblasts via a Nanoparticle Delivery System. College of Pharmacy, National Taiwan University, Taiwan, May 6, 2013
  • Anti-stromal Therapy of Cancer via a Taxane Nanoparticle. 2013 International Advanced Drug Delivery Symposium, Taiwan, May 2, 2013
  • Tumor Stroma Targeting by a Polymeric Conjugate of Docetaxel. Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, March 6, 2013
  • Enhanced Cancer Chemotherapy by Nanomedicine. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, March 4, 2013
  • Nanoparticle Approaches for Targeting Drugs to Tumors. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON January 14, 2013
  • Cellax Drug Delivery Technology.  BioFinance, Toronto, ON, May 29, 2012 
  • Cellax, a proprietary nanoparticle formulation for docetaxel to treat advanced cancers. OICR High Impact Clinical Trials Program Annual Scientific Meeting. OICR, Toronto, ON 2012
  • Realizing Personalized Treatments for Cancer:  Development of Theranostic Polymeric Nanoparticles. University of California, San Diego, CA, USA, 2011
  • Nanomedicine Becomes Personal: Multifunctional Nanoparticles for Targeted Drug Delivery and Early Prediction of Therapeutic Effect. National Tsing Hua University, National Cheng Kung University Hospital and Industrial Technology Research Institute. Taiwan, 2011
  • Thermosensitive Liposomes for Targeted Drug Delivery to Tumors. TTY Pharmaceuticals, Taipei, Taiwan, 2011 
  • Thermosensitive Liposomes: A Story of Evolution of Nanomedicine. National Taiwan University and  Taipei Medical University. Taipei, Taiwan, 2011